Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study

Autor: Katrine K, Hedengran, Dick, Nelson, Malene R, Andersen, Steen, Stender, Pal B, Szecsi
Rok vydání: 2015
Předmět:
Zdroj: The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 29(9)
ISSN: 1476-4954
Popis: To investigate hepcidin during pregnancy, delivery and postpartum in women with sufficient iron supplementation.Hepcidin was measured using LC-MS spectroscopy in 37 women during pregnancy, delivery and postpartum period in this longitudinal study.Hepcidin was low during pregnancy and increased at delivery and postpartum. No correlations with inflammatory markers or iron metabolism were observed during pregnancy; at delivery a correlation with inflammatory markers was observed.During pregnancy, in women with sufficient iron supplementation, hepcidin is low and does not reflect iron status. During delivery and the postpartum period, hepcidin functions as a marker of inflammation.
Databáze: OpenAIRE