Induction of cytodifferentiation in C3H/10T1/2 mouse embryo cells by X-irradiation and benzo(a)pyrene
Autor: | D L, Guernsey, S W, Leuthauser, M J, Koebbe |
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Rok vydání: | 1985 |
Předmět: | |
Zdroj: | Cell differentiation. 16(3) |
ISSN: | 0045-6039 |
Popis: | 5-Azacytidine has been reported to induce adipogenesis and myogenesis in C3H/10T1/2 mouse cells. Additionally, this agent will produce neoplastic transformation of C3H/10T1/2 cells. Very little other data is available regarding induction of differentiation by oncogenic agents. We report here that benzo(a)pyrene and X-irradiation induce a consistent frequency of adipogenesis in C3H/10T1/2 cells. The frequency of induced differentiation is similar to the frequency of the transformation event caused by these agents. |
Databáze: | OpenAIRE |
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