Induction of cytodifferentiation in C3H/10T1/2 mouse embryo cells by X-irradiation and benzo(a)pyrene

Autor: D L, Guernsey, S W, Leuthauser, M J, Koebbe
Rok vydání: 1985
Předmět:
Zdroj: Cell differentiation. 16(3)
ISSN: 0045-6039
Popis: 5-Azacytidine has been reported to induce adipogenesis and myogenesis in C3H/10T1/2 mouse cells. Additionally, this agent will produce neoplastic transformation of C3H/10T1/2 cells. Very little other data is available regarding induction of differentiation by oncogenic agents. We report here that benzo(a)pyrene and X-irradiation induce a consistent frequency of adipogenesis in C3H/10T1/2 cells. The frequency of induced differentiation is similar to the frequency of the transformation event caused by these agents.
Databáze: OpenAIRE