Scandium(III) triflate catalyzed 1,4-addition of cyano group to enones using tetraethylammonium cyanide as the cyanide source

Autor:	Samikannu, Ramesh, Appaswami, Lalitha
Rok vydání:	2013
Předmět:	Chalcones Cyanides Molecular Structure Tetraethylammonium Stereoisomerism Ketones Scandium
Zdroj:	Acta chimica Slovenica. 60(3)
ISSN:	1318-0207
Popis:	A novel and practical method has been developed for the synthesis of β-cyanoketones using tetraethylammonium cyanide (Et4NCN, TEACN) / Sc(III) triflate and chalcones without the liberation of toxic HCN gas. Availability, safety, easy handling of the reagents, mild conditions of the reaction and high yields, make this method an attractive protocol for the direct synthesis of cyano substituted 1,4-adducts from enones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::71bdaf42c06ccadf293bae12bd3396cb https://pubmed.ncbi.nlm.nih.gov/24169725 Zobrazit plný text záznamu