| Autor: |
Z S, Alekberova, V Ia, Madanat, I S, Polianskaia, T B, Prokaeva |
| Rok vydání: |
1993 |
| Předmět: |
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| Zdroj: |
Terapevticheskii arkhiv. 65(5) |
| ISSN: |
0040-3660 |
| Popis: |
Twenty-three patients with Behçet's disease (BD) meeting the criteria of the international group for classification and diagnosis of BD (17 men and 6 women) were typed for HLA antigens class 1. The patients group was multinational, of them 19 were Caucasoids and 4 Mongoloids. It was shown that HLA B5 in Caucasoids occurred more frequently vs normal controls (73.7% and 15.5%, respectively). Under the correction of the antigens number up to 21, the differences continued to be statistically high. Characteristic for B5 antigen was a high relative risk and close association with the disease. In antigen group B5 + B35 the relative risk and association power grew still higher. The B5 positive group statistically more frequently had superficial thrombophlebitis and less frequently gastrointestinal involvement. It is concluded that class 1 HLA antigens, B5 in particular, are closely associated with BD in CIS countries. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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