Prospective evaluation of a 5 × 4 Gy prescription for palliation of canine nasal tumors

Autor: Birgitte, Tan-Coleman, Jarred, Lyons, Craig, Lewis, Mona, Rosenberg, Azucena, Ruiz
Rok vydání: 2012
Předmět:
Zdroj: Veterinary radiologyultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. 54(1)
ISSN: 1058-8183
Popis: We evaluated the efficacy of palliative radiation therapy using 5 × 4 Gy given daily in 18 dogs with nasal tumors. Dogs with malignant nasal tumors were evaluated for response rate, response duration, and survival. Seventy-eight percent of the dogs achieved complete resolution of clinical signs, and 16.5% had partial resolution of their signs. Overall median response duration for all dogs was 178 days after one course of radiation therapy. Six dogs received a second course of therapy when their disease progressed using the same daily 5 × 4 Gy scheme, and all six responded for a median time of 129.5 days for an overall median survival time in these six dogs of 309 days. Based on these results, a radiation prescription of 5 × 4 Gy appears to be useful palliatively in dogs with a malignant nasal tumor.
Databáze: OpenAIRE