| Autor: |
Jian-wei, Liang, Zhi-xiang, Zhou, Qian, Liu, Jian-jun, Bi, Zheng, Wang, Xing-mao, Zhang, Ping, Zhao |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Zhonghua zhong liu za zhi [Chinese journal of oncology]. 32(9) |
| ISSN: |
0253-3766 |
| Popis: |
To evaluate the prognostic factors for patients who underwent curative resection of pulmonary metastases from colorectal cancer.The clinicopathological data of 60 patients with pulmonary metastases from colorectal carcinoma who underwent a radical pulmonary metastasectomy between February 1985 and December 2004 at the Cancer Hospital of Chinese Academy of Medical Sciences were retrospectively reviewed and analyzed.The overall 5-year survival rate was 43.7% after pulmonary excision and 74.0% after colorectal resection. Three factors were identified as significant by univariate log-rank test for overall survival after pulmonary resection, they were preoperative carcinoembryonic antigen, number of pulmonary metastases (solitary vs. multiple), and hilar and/or mediastinal lymph node metastases (P0.05). Multivariate analysis showed that number of pulmonary metastases (solitary vs. multiple) and hilar and/or mediastinal lymph node metastasis were independent prognostic factors. However, shorter disease-free interval and more number of pulmonary metastases predicted poor prognosis after primary colorectal resection.Pulmonary resection for metastases from colorectal cancer is safe and patients may get long-term survival in selected cases, especially in patients with a solitary pulmonary metastasis and without hilar and/or mediastinal lymph node metastasis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
