| Autor: |
C A, Alvarez Marcos, J L, Llorente Pendás, V, Franco Gutiérrez, M A J A, Hermsen, M P, Franco Albalad, H, Fernández Espina, C, Suárez Nieto |
| Rok vydání: |
2007 |
| Předmět: |
|
| Zdroj: |
Acta otorrinolaringologica espanola. 57(10) |
| ISSN: |
0001-6519 |
| Popis: |
The development of second primary tumors (SPT) in patients with head and neck squamous cell carcinoma (HNSCC) has become an increasingly important factor in clinical treatment decisions.To define favourable clinical characteristics for overall survival, in patients with SP head and neck cancer.Records of 633 patients with SCC treated from 1984 to 2004 were reviewed to describe clinical characteristics of the SPT.The overall incidence of SPT was 11%. The incidence of the index tumors was as follows: supraglottic cancer 21% and oral cancer 16%. The most common SPT occurred in head and neck area in 47%, lung in 32% and esophagus in 11%. Second primary was associated with a poor 5 years survival in patients with HN-SCC (23 versus 53% in control group).Because of the high rate of second primary tumors, protocols including chemoprophylaxis should be investigated. Prevention and early detection are indicated. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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