| Autor: |
M E, Willy, R A, Woodward, V B, Thornton, A V, Wolff, B M, Flynn, J L, Heath, Y S, Villamarzo, S, Smith, W J, Bellini, P A, Rota |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
Laboratory animal science. 49(1) |
| ISSN: |
0023-6764 |
| Popis: |
A measles outbreak in a facility housing Old World nonhuman primates developed over a 2-month period in 1996, providing an opportunity to study the epidemiology of this highly infectious disease in an animal-handling setting.Serum and urine specimens were collected from monkeys housed in the room where the initial measles cases were identified, other monkeys with suspicious measles-like signs, and employees working in the affected areas. Serum specimens were tested for measles virus-specific IgG and IgM antibodies, and urine specimens were tested for measles virus by virus isolation or reverse transcriptase-polymerase chain reaction (RT-PCR).A total of 94 monkeys in two separate facilities had evidence of an acute measles infection. The outbreak was caused by a wild-type virus that had been associated with recent human cases of acute measles in the United States; however, an investigation was unable to identify the original source of the outbreak. Quarantine and massive vaccination helped to control further spread of infection.Results emphasize the value of having a measles control plan in place that includes a preventive measles vaccination program involving human and nonhuman primates to decrease the likelihood of a facility outbreak. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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