Foetal haemoglobin in Nigerian children with sickle cell anaemia. Effect on haematological parameters and clinical severity

Autor: O J, Fatunde, A B, Scott-Emuakpor
Rok vydání: 1992
Předmět:
Zdroj: Tropical and geographical medicine. 44(3)
ISSN: 0041-3232
Popis: The relationship of foetal haemoglobin (HbF) to several clinical and haematological parameters in 86 children aged 5 to 16 years who had sickle cell anaemia (SCA) has been examined. The mean HbF level was 6.8 +/- 3.6%. Higher HbF values were significantly associated with fewer blood transfusions, fewer hospital admissions and higher rate of hepatomegaly. A trend for children with higher HbF levels to have better physical development and a more normal haemogram was also noted though this was not statistically significant.
Databáze: OpenAIRE