| Autor: |
M J, Drittij-Reijnders, J P, Sels, M, Rouflart, H H, Thijssen |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
European journal of clinical nutrition. 48(7) |
| ISSN: |
0954-3007 |
| Popis: |
Parenteral nutrition may affect the patient's vitamin K status. This imposes a risk when using drugs that interfere with the vitamin K-dependent clotting factor synthesis, such as N-methyl-thiotetrazole-containing cephalosporins. Intravenous lipid emulsions based on plant oils may contain phylloquinone (vitamin K1). We estimated the vitamin K1 content of the intravenous lipid emulsion product Intralipid (20%), an emulsion based on soybean oil, and estimated the vitamin K1 status of recipient patients. The emulsion was found to contain 0.6-0.7 micrograms/ml of the vitamin. Patients supplied with the product per continuous intravenous infusion, showed a steady increase of their plasma vitamin K1 levels, 3-30-fold over 4 days of infusion. In conclusion, the study shows that fat emulsions prepared from plant oils may contain vitamin K1 in sufficient amounts to meet the daily requirement. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
