| Autor: |
L L, Smrkovski, R L, Buck, C S, Rodriguez, M T, Wooster, J L, Mayuga, D, Rivera |
| Rok vydání: |
1982 |
| Předmět: |
|
| Zdroj: |
The Southeast Asian journal of tropical medicine and public health. 13(4) |
| ISSN: |
0125-1562 |
| Popis: |
A field study was conducted on the island of Mindoro, Republic of the Philippines in which over 800 persons were screened for malaria and approximately 8% were found positive. The in vitro microtechnique was used to test for sensitivity to chloroquine, amodiaquine, mefloquine and quinine in 20 slide-confirmed P. falciparum cases. Sixteen of these cases were also followed for in vivo chloroquine sensitivity. Four cases showed in vitro resistance to chloroquine; 2 also showed resistance to quinine. All showed in vitro sensitivity to mefloquine and amodiaquine. The results of in vivo test were consistent with either a sensitive (S) or R-1, resistant response to chloroquine. Taken together, the in vitro and in vivo chloroquine tests indicate 4 cases of chloroquine resistance at the R1 level. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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