| Autor: |
Luana Beatriz, Dos Santos Nascimento, Paula Fernandes, de Aguiar, Marcos Vinicius, Leal-Costa, Marcela Araújo Soares, Coutinho, Maria Paula Gonçalves, Borsodi, Bartira, Rossi-Bergmann, Eliana Schwartz, Tavares, Sônia Soares, Costa |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Phytochemical analysis : PCA. 29(3) |
| ISSN: |
1099-1565 |
| Popis: |
The medicinal plant Kalanchoe pinnata is a phenolic-rich species used worldwide. The reports on its pharmacological uses have increased by 70% in the last 10 years. The leaves of this plant are the main source of an unusual quercetin-diglycosyl flavonoid (QAR, quercetin arabinopyranosyl rhamnopyranoside), which can be easily extracted using water. QAR possess a strong in vivo anti-inflammatory activity.To optimize the aqueous extraction of QAR from K. pinnata leaves using a three-level full factorial design.After a previous screening design, time (xThe optimal heating times for extract yield and QAR content were similar in two-dimensional (2D) surface responses (between 12.8 and 30 min), but their optimal extraction temperatures were ranged between 40°C and 50°C for QAR content and 30°C and 38°C for extract yield. A compromise region for both parameters was at the mean points that were 40°C for the extraction temperature and 18 min for the total time.The optimized process is faster and spends less energy than the previous one (water; 30 min at 55°C); therefore is greener and more attractive for industrial purposes. This is the first report of extraction optimization of this bioactive flavonoid. Copyright © 2018 John WileySons, Ltd. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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