Association between cycle threshold (C
| Autor: | Juan Pablo, Ramirez-Hinojosa, Yunuen, Rodriguez-Sanchez, Angel Kaleb, Romero-Gonzalez, Marisol, Chavez-Gutierrez, Nelly Raquel, Gonzalez-Arenas, Aurora, Ibarra-Arce, Sara, Arroyo-Escalante, Beatriz, Zavaleta-Villa, Moises, Leon-Juarez, Victor Javier, Cruz-Holguin, Luz Elena, Espinosa de Los Monteros-Perez, Angelica, Olivo-Diaz, Rigoberto, Hernandez-Castro, Lourdes, Suarez-Roa, Hector, Prado-Calleros, Octavio, Sierra-Martinez, Guillermina, Avila-Ramirez, Ana, Flisser, Pablo, Maravilla, Mirza, Romero-Valdovinos |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Inpatients saliva SARS-CoV-2 Health Personnel COVID-19 cycle threshold (C t) Middle Aged Phosphoproteins Severity of Illness Index SARS‐CoV‐2 COVID‐19 COVID-19 Nucleic Acid Testing Coronavirus Nucleocapsid Proteins Humans Female Saliva Asymptomatic Infections Biomarkers Research Articles Aged Research Article |
| Zdroj: | Journal of Medical Virology |
| ISSN: | 1096-9071 |
| Popis: | In‐house assays for the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) by quantitative reverse‐transcription polymerase chain reaction (qRT‐PCR), are feasible alternatives, particularly in developing countries. Cycle threshold (C t) values obtained by qRT‐PCR were compared with clinical and laboratory data from saliva of inpatients with COVID‐19 and asymptomatic health workers (AHW) were studied. Saliva specimens from 58 inpatients confirmed by qRT‐PCR for SARS‐CoV‐2 using nasopharyngeal specimens, and 105 AHW were studied by qRT‐PCR using three sets of primers for the N (N1, N2, and N3) gene of SARS‐CoV‐2, according to the CDC Diagnostic Panel protocol, showing a positivity of 88% for inpatients and 8% for AHW. Bivariate analysis revealed an association between C t |
| Databáze: | OpenAIRE |
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