[Detecting the haplotype of three Y-STR loci by fluorescent multiplex amplification]

Autor: Xiao-Yan, Lin, Lei, Wang, Bao-Long, Yuan, Chang-Jun, Feng, Dai-Xin, Huang
Rok vydání: 2006
Předmět:
Zdroj: Fa yi xue za zhi. 22(2)
ISSN: 1004-5619
Popis: To establish a fluorescent multiplex PCR system for typing Y-STR loci Y-GATA-A7.1, DYS456 and DYS443, and investigate their haplotype frequencies in Chinese Han population.203 unrelated males of Han population living in Zhengzhou were typed by fluorescent multiplex amplification system and ABI 3100 genetic analyzer.In Zhengzhou Han population, 5,6 and 6 different alleles were observed for Y-GATA-A7.1, DYS456 and DYS443 loci, and their gene diversity (GD) were 0.669 2, 0.583 9 and 0.705 3 respectively. A total of 44 different haplotypes formed by these three loci was identified and the haplotype diversity (HD) reached 0.952 3.The fluorescent multiplex system for these three Y-STR loci will be very powerful for forensic individual identification and paternity testing in Chinese Han population.
Databáze: OpenAIRE