Recent Update on Targeting

Autor: Ritapa, Chaudhuri, Semantee, Bhattacharya, Jyotirmayee, Dash, Santanu, Bhattacharya
Rok vydání: 2020
Předmět:
Zdroj: Journal of medicinal chemistry. 64(1)
ISSN: 1520-4804
Popis: Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-quadruplex (G4) structures that are overrepresented in gene promoters. The structural polymorphism and physicochemical properties of these non-Watson-Crick G4 structures make them important targets for drug development. The guanine-rich nuclease hypersensitivity element III
Databáze: OpenAIRE