Arrest of respiration induced by polypeptide antibiotics
Autor: | V, Sobek |
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Rok vydání: | 1982 |
Předmět: | |
Zdroj: | Arzneimittel-Forschung. 32(3) |
ISSN: | 0004-4172 |
Popis: | Polymyxin B affects neuromuscular transmission by blocking acetylcholine receptors. Its action is thus post-synaptic and the neuromuscular block has no antagonists. Polymyxin B causes neostigmine resistance to d-tubocurarine blockade and calcium resistance to the blockade evoked by aminoglycosidic antibiotics. Thus it increases the possibility of definitive arrest of respiration. |
Databáze: | OpenAIRE |
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