Genetic Manipulation of CB1 Cannabinoid Receptors Reveals a Role in Maintaining Proper Skeletal Muscle Morphology and Function in Mice

Autor:	Zoltán, Singlár, Nyamkhuu, Ganbat, Péter, Szentesi, Nomin, Osgonsandag, László, Szabó, Andrea, Telek, János, Fodor, Beatrix, Dienes, Mónika, Gönczi, László, Csernoch, Mónika, Sztretye
Rok vydání:	2022
Zdroj:	International journal of molecular sciences. 23(24)
ISSN:	1422-0067
Popis:	The endocannabinoid system (ECS) refers to a widespread signaling system and its alteration is implicated in a growing number of human diseases. Cannabinoid receptors (CBRs) are highly expressed in the central nervous system and many peripheral tissues. Evidence suggests that CB1Rs are expressed in human and murine skeletal muscle mainly in the cell membrane, but a subpopulation is present also in the mitochondria. However, very little is known about the latter population. To date, the connection between the function of CB1Rs and the regulation of intracellular Ca
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::6f96a91d67fc942bc8bb210cb33effa5 https://pubmed.ncbi.nlm.nih.gov/36555292 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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