| Autor: |
Ikuhiro, Takashima, Yoshihiro, Seto, Ichiro, Nagamine, Yasuhide, Kegoya, Atsunori, Kodoi, Hirofumi, Nakayama |
| Rok vydání: |
2005 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 32(4) |
| ISSN: |
0385-0684 |
| Popis: |
A 72-year-old woman underwent total gastrectomy for CA19-9 producing gastric cancer. TS-1 was administered for recurrent gastric cancer because the duodenal stump was histologically positive and the serum CA19-9 level elevated after temporary regression. The dose was reduced from 80 mg/body/day to 50 mg/body/day because of grade 3 neutropenia. One course consisted of consecutive administration for 28 days followed by 14 days' rest. Upon the completion of the second course, the serum CA19-9 level became within normal limits, and no recurrence nor remarkable adverse reaction has been recognized for 6 courses. Adjuvant use of TS-1 for gastric cancer is ongoing as clinical trials, however, the incidence of adverse reaction does not seem to be negligible with administration of the recommended dose. Low-dose administration of TS-1 is thought to be one effective method of postoperative adjuvant chemotherapy for gastric cancer. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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