| Autor: |
J, Zervas, M, Mavrikakis, K, Kehayoglou, C, Constantopoulos, M, Toubis |
| Rok vydání: |
1986 |
| Předmět: |
|
| Zdroj: |
Clinical and experimental rheumatology. 4(4) |
| ISSN: |
0392-856X |
| Popis: |
The distribution frequencies of HLA-A and B antigens was determined in 94 maturity onset diabetics (40 with CSP and 54 without CSP), as well as in 400 unrelated age- and sex-matched Greek controls. The standard NIH technique was used for tissue typing. There was an increased prevalence of the antigen B27 only in diabetics with CSP (35%) when compared either to the controls (6.8%) or to diabetics without CSP (9.2%). The calculated p-corrected values were Pc = 0.00027 and Pc greater than 0.005 respectively. These findings indicate that the MHC in man may control the genetic susceptibility of a subgroup of insulin-independent diabetics to develop CSP. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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