| Autor: |
Xiao-Fang, Gao, Shui-Ming, Wang, Rui-Yun, Peng, Hong-Yan, Zuo, Li-Feng, Wang, Ya-Bing, Gao, Ji, Dong, Zhen-Tao, Su |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Zhonghua nan ke xue = National journal of andrology. 16(1) |
| ISSN: |
1009-3591 |
| Popis: |
To explore the changes in the expressions of the tight junction related protein occludin and junctional adhesion molecule-1 (JAM-1) of the blood-testis barrier and their significance in rats after microwave radiation.Eighty male Wistar rats were exposed to microwave radiation with average power density of 0, 10, 30 and 100 mW/cm2 for five minutes, and dynamic changes in the expressions of testicular occludin and JAM-1 were observed by Western blot and image analysis at 6 h, 1 d, 3 d, 7 d and 14 d after the radiation.There was a significant down-regulation in the expression of the occludin protein at 3 - 7 d, 6 h - 7 d and 6 h - 14 d (P0. 05), as well as in that of JAM-1 at 3 - 7 d, 1 - 7 d and 1-14 d (P0.05) after exposure to 10, 30 and 100 mW/cm2 microwave radiation.The decreased protein expressions of occludin and JAM-1 may play an important role in the microwave radiation induced-damage to the blood-testis barrier. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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