[Retroviral long terminal repeats: structure and function]
| Autor: | Eva, Lospitao, Africa, Holguín, Vicente, Soriano |
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| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Medicina clinica. 121(2) |
| ISSN: | 0025-7753 |
| Popis: | Characteristic genetic sequences, named as LTR, are present at the end of retroviral genomes. They are involved in the integration of viral nucleic acid into chromosomes of cell host. In addition, LTR modulates the transcription of retroviral genes and, in this form, determine their virulence. LTR from distinct HIV-1 subtypes show structural differences which may result in distinct biological behaviors and, ultimately, different disease progression. |
| Databáze: | OpenAIRE |
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