| Autor: |
A A, Osmolovskiĭ, V G, Kreĭer, N A, Baranova, A V, Kurakov, N S, Egorov |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Prikladnaia biokhimiia i mikrobiologiia. 49(6) |
| ISSN: |
0555-1099 |
| Popis: |
The conditions for the submerged and solid-state cultivation of the micromycete Aspergillus ochraceus VKM F-4104D, producing extracellular proteinases that activate protein C in human blood plasma, were optimized. It is shown that the protein C-activating activity of the micromycete in a solid-state culture was 1.5-3.5 times higher than in a submerged culture (as calculated per milliliter of culture medium). Among the extracellular proteins secreted by A. ochraceus VKM F-4104D during submerged and solid-state cultivation, a protein C-activating proteinase with a pI of 6.0-6.3 was identified. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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