| Autor: |
A N, Kanev, N V, Shalunova, S V, Netesov, O N, Iastrebova, E E, Musina, N G, Bocharova, V P, Mishin, N N, Kiselev, A V, Shystov, M A, Smerdova, T A, Bektimirov |
| Rok vydání: |
2000 |
| Předmět: |
|
| Zdroj: |
Voprosy virusologii. 45(4) |
| ISSN: |
0507-4088 |
| Popis: |
A panel of anti-HCV sera (lot 03HC) was prepared from human sera obtained at blood transfusion centers and infectious hospitals. Donor sera and high-titer sera from patients infected with HCV were used. For positive samples, specific sera reactive with the core and/or NS proteins of HCV 1b and 2 were selected. Positive sera were standardized by the concentrations of IgG with a pool of negative sera containing no HBsAg and antibodies to HIV, HCV, and syphilis. The sera for the panel were selected and titered in screening and specific tests. The anti-HCV panel includes negative and positive sera with low and high titers. The panel sera are stabilized and can be stored for a short time at room temperature. The anti-HCV panel of sera, lot 02HC, was certified at L. A. Tarasevich Institute for Standardization and Control as anti-HCV reference panel intended for sensitivity, specificity, and stability control of diagnostic systems for detection of antibodies to HCV in Russia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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