Stabilisation of eudesmane cation by tryptophan 334 during aristolochene synthase catalysis

Autor:	Athina, Deligeorgopoulou, Susan E, Taylor, Silvia, Forcat, Rudolf K, Allemann
Rok vydání:	2003
Předmět:	Polyisoprenyl Phosphates Cations Penicillium Tryptophan Sesquiterpenes Eudesmane Isomerases Sesquiterpenes Catalysis
Zdroj:	Chemical communications (Cambridge, England). (17)
ISSN:	1359-7345
Popis:	Analysis of the hydrocarbons produced during catalysis by mutants of aristolochene synthase from Penicillium roqueforti indicated that Trp 334 had a pivotal function for the efficient production of aristolochene from farnesylpyrophosphate most likely by stabilising the intermediate, eudesmane cation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::6ea2c2b90a58ad5e4333df681aae146d https://pubmed.ncbi.nlm.nih.gov/13678181 Zobrazit plný text záznamu