Biomarkers for early detection of risk in female patients with coronary artery disease: pilot study

Autor: Sunita, Mahto, S B, Sharma, S, Dwivedi, D, Puri, R L, Tripathi
Rok vydání: 2014
Předmět:
Zdroj: The Journal of the Association of Physicians of India. 61(5)
ISSN: 0004-5772
Popis: In women with coronary artery disease (CAD), clinical presentation is different enough from men which leads to missed or delayed diagnosis. Biomarkers can be used for assessment of CAD patients. In case control study, we analyzed blood samples of 30 controls, 30 cases of Unstable Angina (UA) and 30 cases of Myocardial Infarction (MI) for Pro-inflammatory markers (hs-CRP, IL-6, ICAM-1) and Pregnancy Associated Plasma Protein-A (PAPP-A). Based on discriminant analysis, hs-CRP is the potential marker to discriminate cases of UA from controls while PAPP-A is the reliable marker which can discriminate the cases of MI from UA and controls.
Databáze: OpenAIRE