| Autor: |
A N, Verkhratskiĭ, N F, Pronchuk, A N, Savchenko |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Fiziologicheskii zhurnal. 37(1) |
| ISSN: |
0201-8489 |
| Popis: |
In isolated, cultured neonatal rat ventricular myocytes calcium current was investigated by whole-cell patch clamp technique. The shift of holding potential values from -100-80 mV to -40 mV caused no significant changes in calcium current potential-dependent and kinetic properties. No calcium current component with preferential steady-state inactivation at membrane potentials ranged between -100 and -60 mV was observed. Calcium current component resistant to classic Ca-antagonists action was not found either. All data listed above permit a conclusion on lack of the low-threshold calcium channels in the membrane of single cultured neonatal rat ventricular myocytes. Possible reasons of the absence of this type of calcium are discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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