Ocular and orbital complications of intraarterial cisplatin. A case report

Autor: H M, Wu, A G, Lee, D E, Lehane, T L, Chi, R A, Lewis
Rok vydání: 1997
Předmět:
Zdroj: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 17(3)
ISSN: 1070-8022
Popis: Despite advances in neurosurgery, radiation oncology, and chemotherapy, the prognosis for glioblastoma multiforme remains poor, with a median survival time of 11-12 months. Cisplatin (cis-diamminedichlorideplatinum II) is one treatment for glioblastoma multiforme. Higher response rates have been achieved by intraarterial (i.a.) infusion than by systemic infusion of this agent. Cisplatin therapy may cause neurologic complications, and i.a. delivery has been reported to cause ocular toxicity. We report a patient who experienced intraorbital and intraocular toxicity following supraophthalmic i.a. injection of cisplatin.
Databáze: OpenAIRE