| Autor: |
Xi-Lin, Niu, Yi, Chen, Yutaka, Shoyama, Kazuo, Ishiwata, Ruriko, Obama, Hiroe, Nakazawa |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Methods in enzymology. 359 |
| ISSN: |
0076-6879 |
| Popis: |
We have presented experimental procedures that examine macrophage-mediated LDL oxidation using Ham's F-10 medium. By comparing iNOS-/- and iNOS+/+ macrophages, an antioxidant effect for NO and a prooxidant effect for IFN-gamma were demonstrated. The methods outlined here should allow for the investigation on the mechanism of in vitro LDL oxidation and how the macrophage-mediated LDL oxidation process is affected by various factors, one of which was the effect of iNOS induction by IFN-gamma. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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