Tetanus antibodies as a marker of potential efficacy of killed polio immunization

Autor:	B D, Schoub, S, Johnson, J M, McAnerney, B J, Vorster
Rok vydání:	1986
Předmět:	Black or African American Poliovirus Poliovirus Vaccine Inactivated Random Allocation South Africa Child Preschool Black People Humans Enzyme-Linked Immunosorbent Assay Tetanus Antitoxin Antibodies Viral Developing Countries Poliomyelitis
Zdroj:	South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 70(5)
ISSN:	0256-9574
Popis:	The use of antibodies to tetanus toxin as a marker of efficacy of parenteral immunization was examined in a randomized sample of 1212 sera representative of the total black infant population of the RSA between 24 and 35 months. All but one of these sera had protective levels of antibodies measured by enzyme-linked immunosorbent assay. In contrast, in a previous study only 59-80% had tritypic immunity to polio and 70-84% mono- or bitypic immunity. Thus, this serological marker was found to be unreliable and some possibilities for this remarkably high level of antitetanus antibodies are considered.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::6dcb0e4d13d0439c52a43d3bd6b7c12d https://pubmed.ncbi.nlm.nih.gov/3018948 Zobrazit plný text záznamu