A convenient method to produce [(14) C]carbon monoxide and its application to the radiosynthesis of [carboxyl-(14) C]celivarone, [carboxyl-(14) C]SSR149744

Autor:	David M, Whitehead, Sascha, Hartmann, Tenzeela, Ilyas, Keith R, Taylor, Andrew D, Kohler, George J, Ellames
Rok vydání:	2012
Předmět:	Carbon Monoxide Barium Isotope Labeling Carbonates Carbon Radioisotopes Radiopharmaceuticals Anti-Arrhythmia Agents Benzofurans
Zdroj:	Journal of labelled compoundsradiopharmaceuticals. 56(2)
ISSN:	1099-1344
Popis:	[carboxyl-(14) C]Celivarone was synthesised from barium [(14) C]carbonate with overall radiochemical yields in the range 49-53%. The synthetic route involves [(14) C]carbonylation methodology, which both decreased the number of synthetic steps and increased the yields obtained from previous synthetic routes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::6d7a28681fffe709b7cc6d76a455e203 https://pubmed.ncbi.nlm.nih.gov/24285280 Zobrazit plný text záznamu Plný text