| Popis: |
White rats and mice were subjected to a single intraperitoneal inoculation with a stable L-form of Streptococcus B (strain 090). The hypothalamus, hypophysis and adrenal cortex of the animals were subsequently studied during one year. Progressive degenerative, inflammatory, necrotic and sclerotic changes found in the system hypothalamus-hypophysis-adrenals were due to the bacteria persistence in these organs leading to the disturbance of hormonal homeostasis and development of the system deficiency. There was also the tendency (in 6-12 months after the inoculation) to intensifying regeneration with partial recovery of the organs function. |
