Anti-ovarian cancer potential of phytocompound and extract from South African medicinal plants and their role in the development of chemotherapeutic agents

Autor: Palanisamy, Chella Perumal, Cui, Bo, Zhang, Hongxia, Panagal, Mani, Paramasivam, Sivagurunathan, Chinnaiyan, Uma, Jeyaraman, Selvaraj, Murugesan, Karthigeyan, Rostagno, Mauricio, Sekar, Vijayakumar, Natarajan, Srinivasa Prabhu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Am J Cancer Res
Popis: Ovarian cancer (OC) accounts for the highest tumor-related mortality among the gynecologic malignancies. Most of the OC patients diagnosed with advanced-stage (III and IV) this situation creates panic and provokes an emergency to discover a new therapeutic strategy. Plants that possess medicinal properties are gaining attention as they are enriched with various chemical compounds that are potential to treat various diseases. It is a prolonged process to provide innovative and significant leads against a range of pharmacological targets for a human disease management system. Though challenges and difficulties are faced in the development of a new drug, the emergence of combinatorial chemistry is providing a new ray of hope and also, the executed effort in discovering the drug, and a chemical compound has been remarkably successful. This review discussed the role of medicinal plants that are native of South Africa in treating the Ovarian Cancer and in drug discovery.
Databáze: OpenAIRE