Cyclocytidine chemotherapy for malignant melanoma

Autor: E M, McKelvey, J S, Hewlett, T, Thigpen, J, Whitecar
Rok vydání: 1978
Předmět:
Zdroj: Cancer treatment reports. 62(3)
ISSN: 0361-5960
Popis: Twenty-nine patients with metastatic malignant melanoma were treated with cyclocytidine, 240 mg/m2/day sc for 10 days. All partients had received extensive prior chemotherapy. Only one patient achieved a partial remission; the overall response rate (complete plus partial) was 4%. Unusual toxic effects associated with cyclocytidine chemotherapy included the delayed onset of thrombocytopenia, orthostatic hypotension, and jaw pain.
Databáze: OpenAIRE