| Autor: |
T, Soto, J, Fernández, A, Dominguez, J, Vicente-Soler, J, Cansado, M, Gacto |
| Rok vydání: |
1998 |
| Předmět: |
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| Zdroj: |
Biochimica et biophysica acta. 1443(1-2) |
| ISSN: |
0006-3002 |
| Popis: |
We have cloned and sequenced the ntp1+ gene that codes for neutral trehalase in the fission yeast Schizosaccharomyces pombe. The ntp1+ gene product (Ntp1p) showed a 45-55% identity with neutral trehalases from other yeasts at the amino acid sequence level. However, in clear contrast to other neutral yeast trehalases so far characterized (which show two cAMP phospho-sites), only one consensus site for cAMP-dependent protein phosphorylation was found in Ntp1p. Northern blot hybridization experiments demonstrated that the Wis-Phh1/Sty1 MAP kinase cascade regulates ntp1+ expression during osmostress. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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