[The Mutated Gene Sequenced by NGS and the Correlation of Their Coexistent Mutual Exclusiveness in NPM1 Mutated Acute Myeloid Leukemia]

Autor: Li, Dai, Zhi-Lin, Wang, Guo-Qiang, Qiu, Yi-Cun, Wu, Xiu-Wen, Zhang, Shan-Shan, Xing, Biao, Wang
Rok vydání: 2021
Předmět:
Zdroj: Zhongguo shi yan xue ye xue za zhi. 29(6)
ISSN: 1009-2137
Popis: To analyze the clinicobiological heterogeneity of NPM1 mutated (NPM1The NGS data based on 112 genes related to blood disease in 238 newly diagnosed patients with NPM1Among all the patients, at least one co-mutation was detected out. The median number per case of the mutated genes, including NPM1Prognoses of AML involving less common NPM1 missense mutations should be stated on a case by case basis. The mutational landscape and co-occurrence and mutual exclusivity correlations of NPM1NPM1突变急性髓系白血病二代测序突变基因谱及共存互斥相关性分析.分析NPM1突变(NPM1收集238例成人初诊NPM1全部NPM1阐述NPM1
Databáze: OpenAIRE