| Autor: |
M M, Fuzik, A Y, Prysyazhnyuk, Y, Shibata, A Y, Romanenko, Z P, Fedorenko, N A, Gudzenko, L O, Gulak, N K, Trotsyuk, Y L, Goroh, O M, Khukhrianska, O V, Sumkina, V A, Saenko, S, Yamashita |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Problemy radiatsiinoi medytsyny ta radiobiolohii. (18) |
| ISSN: |
2304-8336 |
| Popis: |
The objective of this study was to investigate the thyroid cancer incidence in a whole territory of Ukraine and to clear up its age and gender patterns depending on average regional (oblast) thyroid doses from radioactive iodine due to the Chornobyl accident. MATERIALS AND METHODS. On the basis of average accumulated thyroid doses from radioactive iodine the geographical regions of Ukraine with low and high average thyroid doses were identified for a comparative analysis performance. Methods of descriptive epidemiology were used.The level and dynamics of thyroid cancer incidence were analyzed in different gender and age groups (both for attained age and age at the moment of the Chornobyl accident). Results of this study confirmed the radiation excess of thyroid cancer in individuals who were children and adolescents in 1986. Some excess was observed in elder age groups too. Especial situation was observed in female age group 40-49 at the moment of the Chornobyl accident i.e. the age-specific thyroid cancer incidence rates were significantly higher in "high exposure" regions comparing with "low exposure" ones during all years of observation within 1989-2009.A probable radiation excess of thyroid cancer was suggested not only in children and adolescents but also in adult age groups. In elder age groups this excess was less expressed and manifested after a longer period of time. The origin of the phenomenon in female age group of 40-49 is unclear now. Hypothesis of combined effect of radiation and natural changing of hormonal status in this age should be checked in the future studies.Metoju c'ogo doslidzhennja bulo vyvchyty zahvorjuvanist' na rak shhytopodibnoi' zalozy na vsij terytorii' Ukrai'ny ta vyjavyty statevi ta vikovi osoblyvosti zalezhno vid seredn'ooblasnyh doz na shhytopodibnu zalozu vid radioaktyvnogo jodu vnaslidok avarii' na ChAES. Materialy ta metody. Na osnovi serednih nakopychenyh shhytopodibnoju zalozoju doz oprominennja radioaktyvnym jodom geografichni regiony Ukrai'ny dlja provedennja porivnjal'nogo analizu bulo podileno na dvi grupy - z „vysokymy” ta „nyz'kymy” dozamy. V doslidzhenni vykorystovuvalys' metody deskryptyvnoi' epidemiologii'. Rezul'taty. Proanalizovano riven' ta dynamiku zahvorjuvanosti na rak shhytopodibnoi' zalozy v riznyh statevo-vikovyh grupah (vidnosno jak viku na moment diagnozu, tak i pid chas avarii' na ChAES). Pidtverdzheno radiacijnyj eksces u osib, jaki buly dit'my ta pidlitkamy na moment avarii'. Pevnyj eksces sposterigavsja i v starishyh vikovyh grupah. Osoblyva sytuacija mala misce u zhinok vikom 40–49 rokiv na moment avarii', sered jakyh povikovi pokaznyky zahvorjuvanosti na terytorijah z „vysokymy” dozamy buly dostovirno vyshhymy uprodovzh vs'ogo periodu sposterezhennja 1989–2009 rr. Vysnovky. Okrim dytjachyh ta pidlitkovyh grup, rezul'taty doslidzhennja svidchat' pro virogidnyj radiacijnyj eksces u doroslyh. U starishyh vikovyh grupah cej eksces mensh vyrazhenyj ta projavljajet'sja pislja bil'sh tryvalogo chasu. Pohodzhennja zgadanogo fenomenu u zhinok vikom 40–49 rokiv na moment avarii' poky shho zalyshajet'sja nejasnym. U podal'shyh doslidzhennjah slid pereviryty gipotezu kombinovanogo vplyvu radiacii' ta pryrodnyh zmin gormonal'nogo stanu u c'omu vici. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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