Evidence for autonomic nervous system imbalance in women with irritable bowel syndrome

Autor:	M, Heitkemper, R L, Burr, M, Jarrett, V, Hertig, M K, Lustyk, E F, Bond
Rok vydání:	1998
Předmět:	Adult Heart Rate Parasympathetic Nervous System Case-Control Studies Humans Female Vagus Nerve Colonic Diseases Functional Middle Aged Autonomic Nervous System
Zdroj:	Digestive diseases and sciences. 43(9)
ISSN:	0163-2116
Popis:	Autonomic nervous system function was assessed in women with and without irritable bowel syndrome using frequency domain measures of heart rate variability. Women were interviewed and placed into the irritable bowel syndrome (N = 25) group based on history of diagnosis and self-report of current gastrointestinal symptoms. Women in the control group denied a history of chronic gastrointestinal symptoms (N = 15). Women were followed for one menstrual cycle with a symptom diary, and during mid-luteal phase they wore a Holter 24-hr electrocardiograph monitor. Women with irritable bowel syndrome demonstrated significantly lower vagal tone as measured by the high frequency spectrum relative to control women. In addition, women with irritable bowel syndrome had a flattened 24-hr pattern of heart rate variability, with significantly lower levels of vagal tone during sleep. These results suggest that systemic sympathovagal balance may be shifted in a subset of women with irritable bowel syndrome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::6cc7f8eb7fcce3c5e30ec53005ad5ece https://pubmed.ncbi.nlm.nih.gov/9753278 Zobrazit plný text záznamu Full text from SpringerLink