| Popis: |
A long-term (3 week-lasting), double-blind, placebo-controlled study was carried out in order to determine the efficacy of inhaled Plaferon LB (a 6 Kd protein fraction-peptide, obtained by purification of human placental amniotic membrane) in 43 asthmatic children. Study group of patients were receiving daily inhalations (using special nebulizer) of a standard dose of plaferon (5 mg/ml - 3 ml), while in placebo group an inert solution was used. At the end of each trial week the spirometric data of patients were obtained. According to the results of the study, plaferon-inhalation therapy was associated with statistically significant improvement of spirometric values. It may be concluded long-term plaferon treatment provides an effective and safe alternative to traditional bronchodilator drugs in the management of childhood asthma. |
