The effect of selected membrane active substances on erythrocyte deformability

Autor: I, Beder, M, Kittova, A, Mataseje, J, Carsky, Z, Orszaghova, K, Babinska
Rok vydání: 2003
Předmět:
Zdroj: Bratislavske lekarske listy. 104(2)
ISSN: 0006-9248
Popis: Aminoguanidine improved the erythrocyte filterability by 4%, pyridoxyliden-aminoguanidine by 11% and pyridoxal by 13% in healthy subjects. In diabetic patients the aminoguanidine effect on erythrocyte filterability was improved by 7%, PAG effect by 9% and pyridoxal effect by 15% in comparison to the control group. The other investigated haematological variables in both groups were within the range of the physiological standard. All of the tested substances demonstrated a mild protective influence on erythrocyte elasticity both in healthy subjects and diabetic patients. Significant elasticity improvement was obtained only by pyridoxal (p0.01) in patients with diabetes mellitus. (Fig. 4, Ref. 18.).
Databáze: OpenAIRE