[Disseminated sclerosis and retrovirus]

Autor: A, Møller-Larsen, M, Sommerlund, S, Haahr
Rok vydání: 1992
Předmět:
Zdroj: Ugeskrift for laeger. 154(24)
ISSN: 0041-5782
Popis: Multiple sclerosis is a disease characterized by neurologic dysfunction due to focal CNS lesions with demyelination. The cause of the disease is unknown; but it may be due to a virus and/or autoimmune reactions. The latter cause is suspected on account of family- and ethnical studies, the first on account of locally produced antibodies in the cerebrospinal fluid, and also epidemiologic investigations. The newly discovered human retroviruses, especially HTLV-I which is the cause of tropical spastic paraparesis, has been suspected as a possible cause; but this has been disproved by multiple antibody- and PCR-studies. An uncharacterized exogenous or an endogenous retrovirus is still considered to be a possible cause or possibly partial cause of the disease which could be multifactorial.
Databáze: OpenAIRE