Immunohistochemical analysis of c-erbB-2, Bcl-2, p53, p21
| Autor: | Nabiha, Missaoui, Hanene, Landolsi, Sarra, Mestiri, Ahlem, Essakly, Nihed, Abdessayed, Sihem, Hmissa, Moncef, Mokni, Mohamed Tahar, Yacoubi |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Cyclin-Dependent Kinase Inhibitor p21 Adolescent Receptor ErbB-2 Membrane Proteins Hydatidiform Mole Middle Aged Immunohistochemistry Young Adult Ki-67 Antigen Proto-Oncogene Proteins c-bcl-2 Pregnancy Uterine Neoplasms Biomarkers Tumor Humans Female Tumor Suppressor Protein p53 Retrospective Studies |
| Zdroj: | Pathology, research and practice. 215(3) |
| ISSN: | 1618-0631 |
| Popis: | Hydatidiform moles (HM) are characterized by an abnormal proliferating trophoblast with a potential for a malignant transformation. Similar to other human tumors, trophoblastic pathogenesis is likely a multistep process involving several molecular and genetic alterations. The study was performed to investigate the expression patterns of c-erbB-2 and Bcl-2 oncoproteins, p53, p21 |
| Databáze: | OpenAIRE |
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