[Cathepsin B Affects the Activation of Nucleotide-binding Domain and Leucine-rich-repeat-containing Family and Pyrin Domain-containing 3 Inflammasome via Transient Receptor Potential Mucolipin-1]

Autor:	Juan Juan, Duan, Qi Fang, Zhang, Zong Hua, Huang, Hong Mei, Zeng, Hua, Bai
Rok vydání:	2019
Předmět:	Mice Oxidative Stress Transient Receptor Potential Channels Inflammasomes Interleukin-1beta NLR Family Pyrin Domain-Containing 3 Protein Animals Pyrin Domain Gene Silencing Hydrogen Peroxide Microglia Cathepsin B Cell Line
Zdroj:	Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 41(2)
ISSN:	1000-503X
Popis:	Objective To explore the effects of cathepsin B(CTSB)on the activation of nucleotide-binding domain and leucine-rich-repeat-containing family and pyrin domain-containing 3(NLRP3)inflammasome via transient receptor potential mucolipin-1(TRPML1)in cell oxidative stress model and specific gene silencing cell model. Methods BV2 cells cultured in vivo were treated separately or simultaneously with hydrogen peroxide(H
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::6bef87bf14f60e6e52f03f70d754fb59 https://pubmed.ncbi.nlm.nih.gov/31060676 Zobrazit plný text záznamu