Discovery of Novel microRNAs in Aging Caenorhabditis elegans

Autor: Alexandre, de Lencastre, Frank, Slack
Rok vydání: 2015
Předmět:
Zdroj: Methods in molecular biology (Clifton, N.J.). 1343
ISSN: 1940-6029
Popis: The rapid development of deep sequencing technologies over the last few years and concomitant increases in sequencing depth and cost efficiencies have opened the door to a ever-widening range of applications in biology-from whole-genome sequencing, to ChIP-seq analysis, epigenomic and RNA transcriptome surveys. Here we describe the application of deep sequencing to the discovery of novel microRNAs and characterization of their differential expression during adulthood in Caenorhabditis elegans.
Databáze: OpenAIRE