| Autor: |
S, Jayabose, O, Tugal, R, Ruddy, D, Wuest, D, Ciavarella |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
The American journal of pediatric hematology/oncology. 15(3) |
| ISSN: |
0192-8562 |
| Popis: |
We evaluated the safety and efficacy of a new transfusion regimen for children with severe anemia.Twenty-two consecutive patients with severe anemia (hemoglobin5 g/dl) of gradual onset requiring transfusion of packed red blood cells (PRBC) were studied. The transfusion regimen consisted of continuous infusion of PRBC at the rate of 2 cc/kg/h until the desired volume was given. Throughout the transfusion, the patients were closely monitored for any clinical signs of heart failure. The rise in hematocrit per 1 cc of PRBC/kg transfused was computed for each patient.No patient developed any signs of cardiac failure or increase in the heart rate during or after the completion of transfusion. All patients had a decrease in the heart rate by the completion of transfusion. The mean decrease in the heart rate was 28% of the pretransfusion heart rate (range 12-44%). Excluding the four patients with sickle cell anemia, the remaining 18 patients had a mean increase in the hematocrit of 1.04% per 1 cc/kg of PRBC (range 0.85-1.28).We conclude that for children with severe anemia of gradual onset requiring transfusion therapy, continuous transfusion of PRBC at the rate of 2 cc/kg/h is a safe and effective regimen resulting in an increase in the hematocrit of approximately 1% for each 1 cc/kg of PRBC transfused in all patients, except patients with sickle cell anemia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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