| Autor: |
Satoru, Suwa, Manabu, Ogita, Hideki, Ebina, Koichi, Nakao, Yukio, Ozaki, Kazuo, Kimura, Junya, Ako, Teruo, Noguchi, Satoshi, Yasuda, Kazuteru, Fujimoto, Yasuharu, Nakama, Takashi, Morita, Wataru, Shimizu, Yoshihiko, Saito, Atsushi, Hirohata, Yasuhiro, Morita, Teruo, Inoue, Atsunori, Okamura, Toshiaki, Mano, Kazuhito, Hirata, Kengo, Tanabe, Yoshisato, Shibata, Mafumi, Owa, Kenichi, Tsujita, Hiroshi, Funayama, Nobuaki, Kokubu, Ken, Kozuma, Shiro, Uemura, Tetsuya, Toubaru, Keijiro, Saku, Shigeru, Oshima, Kunihiro, Nishimura, Yoshihiro, Miyamoto, Hisao, Ogawa, Masaharu, Ishihara |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
International heart journal. 61(2) |
| ISSN: |
1349-3299 |
| Popis: |
Discordant results have been reported on outcomes of acute myocardial infarction (AMI) patients who present during off-hours.We investigated 3283 consecutive patients with AMI who were selected from the prospective, nationwide, multicenter registry (J-MINUET) database comprising 28 institutions in Japan between July 2012 and March 2014 to determine the current impact of off-hours presentation (defined as weekends, holidays, and weekdays from 8:01 PM to 7:59 AM) at hospitals on long-term clinical outcomes. The primary endpoint was a composite of all-cause death, non-fatal MI, non-fatal stroke, cardiac failure, and urgent revascularization for unstable angina for up to 3 years from the index event.During off-hours, 52% of patients presented. Primary percutaneous coronary intervention was performed in 85% of patients, and the door-to-balloon time was comparable between off-hours and regular hours (74, interquartile range [IQR] 52 to 113 versus 75, IQR 52 to 126 minutes, P = 0.34). Rate of overall primary endpoint overall did not overall significantly differ (25.3% versus 23.5%, log-rank P = 0.26), in patients with ST-elevation myocardial infarction (STEMI) (log-rank P = 0.93) and in patients with non-ST-elevation myocardial infarction (NSTEMI) (log-rank P = 0.14). Multivariate Cox regression analysis showed that off-hours presentation was not significantly associated with long-term clinical events in all cohorts.The impact of presentation during off-hours or regular hours on the long-term clinical outcomes of Japanese patients with AMI is comparable in contemporary practice. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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