Misplaced iron in kwashiorkor

Autor: W S, Dempster, A A, Sive, S, Rosseau, H, Malan, H V, Heese
Rok vydání: 1995
Předmět:
Zdroj: European journal of clinical nutrition. 49(3)
ISSN: 0954-3007
Popis: To determine the presence of radical promoting iron (non-protein-bound or loosely bound or free iron) in the plasma of children with kwashiorkor.The bleomycin assay was employed for the quantitation of free or loosely bound iron.The Red Cross War Memorial Children's Hospital, Cape Town, Tertiary Care.Fifty children on admission with kwashiorkor: six with marasmus and twelve healthy well-nourished controls.Non-protein-bound iron was detected in the plasma of 58% of children with kwashiorkor but was absent in marasmic and healthy well-nourished children.The presence of radical promoting iron supports the hypothesis that a free radical injury probably plays a role in the pathogenesis of kwashiorkor and its removal may improve mortality.
Databáze: OpenAIRE