Primary Effusion Lymphoma (PEL)-Like Lymphoma in a Child With Congenital Immunodeficiency

Autor: Grace K S, Lam, Mohamed, Abdelhaleem, Gino R, Somers, Chaim, Roifman, Stanley, Read, Oussama, Abla
Rok vydání: 2016
Předmět:
Zdroj: Pediatric bloodcancer. 63(9)
ISSN: 1545-5017
Popis: Primary effusion lymphoma (PEL) is a rare lymphoma that occurs more frequently in immunocompromised adults and has a poor survival. We report a 9-year-old female with combined immunodeficiency with an Epstein-Barr virus positive/human herpes virus 8 negative PEL-like lymphoma. The treatment with systemic chemotherapy for non-Hodgkin lymphoma, zidovudine, and interferon-α failed to control disease progression. This is the first reported pediatric case of PEL-like lymphoma. Increased diagnostic awareness and more effective treatment strategies are needed for this rare lymphoma.
Databáze: OpenAIRE