| Autor: |
J A, Bartok, E M, Martin, D L, Pitrak, R M, Novak, K J, Pursell, K M, Mullane, M, Harrow |
| Rok vydání: |
1997 |
| Předmět: |
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| Zdroj: |
Journal of the International Neuropsychological Society : JINS. 3(5) |
| ISSN: |
1355-6177 |
| Popis: |
We studied the integrity of working memory operations in 38 HIV-seropositive and 20 seronegative drug users, using a modified version of the Tower of London task. This new task, the Tower of London-Working Memory version (TOL-WM), includes a delayed-response component in addition to the planning required for successful performance of the standard TOL. Symptomatic HIV-seropositive participants solved significantly fewer TOL-WM problems compared to matched seronegative controls. However, seropositive and seronegative subjects showed similar overall levels of planning efficiency, suggesting that the TOL-WM deficit may be associated primarily with failure to encode or maintain an adequate online memory representation. The results of this study confirm our previous report of a possible working memory deficit in HIV-1 infection and suggest that measures of working memory have particular utility in the evaluation of HIV-related cognitive deficits. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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