Dose-Response Effect of Saccharomyces cerevisiae UFMG A-905 on the Prevention of Asthma in an Animal Model

Autor: Thamires M S, Milani, Camila M, Sandy, Ana Paula Carvalho Thiers, Calazans, Rosana Q, Silva, Vanessa M B, Fonseca, Flaviano S, Martins, Marcos C, Borges
Rok vydání: 2022
Zdroj: Probiotics and antimicrobial proteins.
ISSN: 1867-1314
Popis: Probiotics should be administered in adequate amounts to confer health benefits. Probiotic dose-response studies are still missing. Saccharomyces cerevisiae UFMG A-905 prevented asthma development; however, the ideal dose has not been investigated. We evaluated the optimal dose and administration regimen of S. cerevisiae UFMG A-905 in the prevention of asthma. Male Balb/c mice were sensitized intraperitoneally with ovalbumin (OVA) and challenged with OVA intranasally. Mice received, via gavage, daily or alternate-day S. cerevisiae UFMG A-905. In daily regimen, different concentrations (10
Databáze: OpenAIRE