Metal migration and subunit swapping in ALS-linked SOD1: Zn

Autor: Chad M, Dashnaw, Ao Yun, Zhang, Mayte, Gonzalez, Jordan C, Koone, Bryan F, Shaw
Rok vydání: 2022
Zdroj: The Journal of biological chemistry. 298(12)
ISSN: 1083-351X
Popis: The heterodimerization of WT Cu, Zn superoxide dismutase-1 (SOD1), and mutant SOD1 might be a critical step in the pathogenesis of SOD1-linked amyotrophic lateral sclerosis (ALS). Rates and free energies of heterodimerization (ΔG
Databáze: OpenAIRE