Metal migration and subunit swapping in ALS-linked SOD1: Zn
Autor: | Chad M, Dashnaw, Ao Yun, Zhang, Mayte, Gonzalez, Jordan C, Koone, Bryan F, Shaw |
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Rok vydání: | 2022 |
Zdroj: | The Journal of biological chemistry. 298(12) |
ISSN: | 1083-351X |
Popis: | The heterodimerization of WT Cu, Zn superoxide dismutase-1 (SOD1), and mutant SOD1 might be a critical step in the pathogenesis of SOD1-linked amyotrophic lateral sclerosis (ALS). Rates and free energies of heterodimerization (ΔG |
Databáze: | OpenAIRE |
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